Is chromophobe renal cell carcinoma curable?

The prognosis of chromophobe RCC is better than conventional RCC, even in metastatic disease. Distant metastases are more found in liver and lungs. The studies proved that patients with chromophobe RCC have a good prognosis and survival rates in early stage [20].

Why is it called chromophobe RCC?

Chromophobe RCC was first reported in 1985; its name was derived from the morphologic similarity between the predominant tumor cells in the human tumor to those comprising the experimentally produced rat kidney tumor.

How fast does chromophobe renal cell carcinoma grow?

The researchers found that 98% of the 95 lesions (81 oncocytoma, 14 chromophobe renal cell carcinoma) included in the analysis were diagnosed on biopsy. During a median follow-up of 34 and 25 months, respectively, the annual growth rate was 0.14 cm for oncocytoma and 0.38 cm for chromophobe renal cell carcinoma.

Does chromophobe RCC come back?

Most primary cases are localized at presentation and are treated with partial or radical nephrectomy with curative intent. However, renal cell carcinoma (RCC) is known for its potential recurrence, sometimes several years after initial management.

Is chromophobe renal cell carcinoma aggressive?

Clinical behavior of chromophobe renal cell carcinoma is less aggressive than that of clear cell renal cell carcinoma, independent of Fuhrman grade or tumor size. Virchows Arch.

What does chromophobe mean?

not readily absorbing stains
: not readily absorbing stains : difficult to stain chromophobe tumors.

What is a chromophobe adenoma?

chromophobe adenoma (chromophobic adenoma) a pituitary adenoma composed of cells that lack acidophilic or basophilic granules; this is the same entity as the more precisely named null-cell a.

How quickly does renal cell carcinoma grow?

The average tumor growth rate was 0.80 (range, 0.16-3.80) cm/year. Clear cell carcinoma (0.86 cm/year) tended to grow faster than papillary cell carcinoma (0.28 cm/year) (P = 0.066).

How quickly do kidney tumors grow?

The growth rate of renal masses in that study was 0.28 cm/year (range 0.09–0.86 cm/year). A somewhat faster growth rate was observed in the subgroup of patients with pathologically confirmed renal cancer (0.4 cm/year, range 0.42–1.6 cm/year).

Is chromophobe renal cell carcinoma?

Chromophobe renal cell carcinoma is a rare type of kidney cancer that forms in the cells lining the small tubules in the kidney. These small tubules help filter waste from the blood, making urine. As the different types of kidney cancer are very distinct, characterizing and understanding each type is important.

Where is chromophobe found?

Chromophobe cells are one of three cell stain types present in the anterior and intermediate lobes of the pituitary gland, the others being basophils and acidophils. One type of chromophobe cell is known as amphophils. Amphophils are epithelial cells found in the anterior and intermediate lobes of the pituitary.

Is there a cure for renal cell carcinoma?

The only curative treatment of renal cell carcinoma is surgical; however, approximately 30% of patients present with evidence of metastatic disease at the time of diagnosis.

Freebase(0.00 / 0 votes)Rate this definition: The term chromophobe, refers to histological structures which do not stain readily, and thus appear more relatively pale under the microscope—hence their “fear” of “color”. Chromophobe cells, also known as amphophils, are epithelial cells found in the anterior and intermediate lobes of the pituitary.

Is renal cell carcinoma really radioresistant?

Renal cell carcinoma metastases are regarded as radioresistant tumors and surgery is recommended. However, since metastatic renal cell carcinoma has poor prognosis and is composed of abundant blood vessels, it is sometimes difficult for clinicians to choose surgical therapy.

What is the cause of kidney cancer?

Kidney cancer is a disease where the cells of the kidney turn cancerous and grow out of control. It is also called renal cancer. The exact cause of is unknown, but there are numerous risk factors such as smoking, drinking alcohol, obesity, high blood pressure, etc.