What is cardene drip used for?

Nicardipine is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Nicardipine is called a calcium channel blocker. It works by relaxing blood vessels so blood can flow more easily.

How do you titrate a cardene drip?

Administration: Nicardipine (Cardene) 50 mg in 250 ml NS (0.2 mg/ml) starting at 5mg/hr (25 ml/hr) IV infusion. Titrate to effect by increasing the rate of administration by 2.5 mg/hr every 5 minutes to a maximum of 15 mg/hr until desired blood pressure reduction is achieved.

What is the difference between nifedipine and nicardipine?

Nicardipine is a second-generation dihydroperidine calcium antagonist that unlike nifedipine causes little, if any, increase in heart rate. Nicardipine produces slower, and more prolonged decrease in BP than nifedipine, and therefore appears to be better tolerated.

Can nifedipine be given IV?

In conclusion, the intravenous infusion of nifedipine in a dose 1.25 mg/h, seems to control the hypertensive phases of blood pressure, without dropping to any unduly low level, risking undesirable side effects in elderly hypertensive patients during perioperative period.

Does cardene drip lower heart rate?

By slowing calcium influx into cardiac muscle cells, calcium channel blockers tend to reduce the force of cardiac contraction, thus reducing cardiac work and the vigor of the heart beat.

Does cardene slow heart rate?

In general, no detrimental effects on the cardiac conduction system have been seen with Cardene I.V. During acute electrophysiologic studies, it increased heart rate and prolonged the corrected QT interval to a minor degree.

What do you need to start a cardene drip?

Recommended Dosing Cardene I.V. 20 mg in 200 mL (0.1 mg/mL): Initiate therapy at 50 mL/hr (5 mg/hr).

How do I start nicardipine drip?

Initial dose: Treatment should start with the continuous administration of nicardipine at a rate of 3-5 mg/h for 15 minutes. Rates can be increased by increments of 0.5 or 1 mg every 15 minutes. The infusion rate should not exceed 15 mg/h.

What is the brand name for nicardipine?

BRAND NAME(S): Cardene. USES: Nicardipine is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Nicardipine is called a calcium channel blocker.

What class of drug is nicardipine?

Nicardipine is in a class of medications called calcium channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. It controls chest pain by increasing the supply of blood and oxygen to the heart.

How is nifedipine administered?

Nifedipine comes as a capsule and an extended-release (long-acting) tablet to take by mouth. The capsule is usually taken three or four times a day. The extended-release tablet should be taken once daily on an empty stomach, either 1 hour before or 2 hours after a meal.

Which calcium channel blocker can be given IV?

Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension.

What is the titrate dose of Cardene I.V?

Cardene I.V. is intended for intravenous use. Titrate dose to achieve the desired blood pressure reduction. Individualize dosage depending on the blood pressure to be obtained and the response of the patient. Cardene I.V. 20 mg in 200 mL (0.1 mg/mL): Initiate therapy at 50 mL/hr (5 mg/hr).

When to start oral nicardipine or Cardene I.V.?

If treatment includes transfer to an oral antihypertensive agent other than oral nicardipine, initiate therapy upon discontinuation of Cardene I.V. Premixed Injection. If oral nicardipine is to be used, administer the first dose 1 hour prior to discontinuation of the infusion.

How to check Cardene i.v.premixed injection?

Inspect Cardene I.V. Premixed Injection visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Check the container for minute leaks prior to use by squeezing the bag firmly; ensure that the seal is intact. If leaks are found, discard solution as sterility may be impaired.

How often do you change the infusion site for Cardene?

Administer Cardene I.V. by a central line or through a large peripheral vein. Change the infusion site every 12 hours if administered via peripheral vein [see Warnings and Precautions ( 5.5 )].