How do you administer a C1 esterase inhibitor?

CINRYZE ® (C1 esterase inhibitor [human]) is administered by intravenous (or IV) injection, meaning it is injected into a vein in the arm. You can choose to have your injection administered by a healthcare provider or caregiver, or a healthcare provider can show you how to give it to yourself.

What is Cinryze used to treat?

Cinryze is FDA-approved to prevent angioedema attacks in adults and in children ages 6 years and older. Angioedema attacks occur in people with a condition called hereditary angioedema (HAE). HAE is a genetic condition that causes swelling attacks. This swelling usually occurs in your arms, legs, face, or intestines.

What medication treats hereditary angioedema?

ICATIBANT (GENERIC) is a bradykinin B2 receptor antagonist indicated for treatment of acute attacks of Hereditary Angioedema (HAE) in adults 18 years of age and older. Generic Icatibant is delivered by subcutaneous injection and is approved for self-administration. Multiple manufacturers offer Generic Icatibant.

What is C1 esterase inhibitor deficiency?

Hereditary angioedema, otherwise known as C1 esterase deficiency, is defined by recurrent episodes of angioedema without urticaria or pruritus. These skin conditions typically involve the legs, hands, face, upper respiratory tract, as well as gastrointestinal tract.

Can kalbitor be self administered?

No, you shouldn’t self-inject Kalbitor. Kalbitor can cause a serious allergic reaction called anaphylaxis. * So only a healthcare professional should give you the injections. In fact, you’ll need to receive them in a medical setting where anaphylaxis and hereditary angioedema (HAE) can be treated.

How is BERINERT administered?

Berinert is given by intravenous infusion (slowly into the vein), as soon as possible in people experiencing an acute attack of HAE. It can either be given by a trained nurse or doctor or people (or their caregivers) can be taught how to self-administer it themselves.

How is Cinryze made?

How is CINRYZE made? CINRYZE is made from purified human blood. It is collected from plasma donors at licensed collection centers throughout the United States. Then it goes through a complex purification process designed to reduce the chance that certain viruses could be transmitted.

What are HAE medications?

FIRAZYR is a medicine used to treat acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older.

What can trigger hereditary angioedema?

Exposure to common foods or environmental factors can trigger hereditary angioedema attacks. These include seafood, shellfish, nuts, eggs, milk, animal hair, insect bites, pollen, sun, extreme warm or cold weather, and latex.

What does complement C1 inhibitor protein mean?

Complement C1 esterase inhibitor is a man-made form of a protein in blood that helps control swelling in the body. People with a condition called hereditary angioedema do not have enough of this protein.

What is C1 inhibitor?

View/Edit Mouse. C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement system to prevent spontaneous activation.

What is C1 and C2 esterase?

C1 esterase inhibitor . C1 esterase inhibitor (C1-INH) is a protein found in the fluid part of your blood . It controls a protein called C1, which is part of the complement system. This system is a group of proteins that move freely through your bloodstream. The proteins work with your immune system and play a role in the development of inflammation.