What is sulfisoxazole used for?

Sulfisoxazole is used to treat or prevent infections in many different parts of the body. It belongs to the group of medicines known as sulfonamide antibiotics. It works by preventing the growth of bacteria. However, this medicine will not work for colds, flu, or other virus infections.

What is the mechanism of action of sulfisoxazole?

Sulfisoxazole is a competitive inhibitor of the enzyme dihydropteroate synthetase. It inhibits bacterial synthesis of dihydrofolic acid by preventing the condensation of the pteridine with para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase.

Is a combination of erythromycin and Sulfisoxazole?

The combination of erythromycin and sulfisoxazole (a sulfa drug) is used to treat certain ear infections caused by bacteria. It usually is used in children. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Does sulfisoxazole block folic acid synthesis?

Mechanism of Action Sulfonamides competitively inhibit the incorporation of PABA into folic acid, thereby preventing the synthesis of folic acid.

How do you take Sulfisoxazole?

Take this medicine with a full glass (8 ounces) of water. Several additional glasses of water should be taken during the day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects. This medicine works best when there is a constant amount in the blood or urine.

What type of antimicrobial agent is Sulfisoxazole?

Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria.

How do tetracyclines work?

Tetracycline interferes with the ability of the bacteria to produce certain vital proteins required for bacterial growth. They target the ribosomal machinery within the bacteria that assembles proteins from amino acids. Due to this mode of action, tetracyclines inhibit bacterial growth rather than killing them.

What is a combination of erythromycin and Sulfisoxazole called?

(erythromycin ethylsuccinate and sulfisoxazole acetyl) Pediazole (erythromycin and sulfisoxazole) is a combination of erythromycin ethylsuccinate, USP, and sulfisoxazole acetyl, USP.

What inhibits folic acid synthesis?

Trimethoprim-sulfonamides are less commonly used than the previously mentioned antibiotics as prophylactic antimicrobials. However, trimethoprim-sulfonamides act synergistically to inhibit the synthesis of folic acid, a compound that is required for microbial DNA production.

Which drug group inhibits folic acid synthesis?

Sulfonamides, a class of antimicrobials that work by inhibiting folate biosynthesis.

What should you know about the drug sulfisoxazole?

Sulfisoxazole (Oral) 1 Commonly used brand name (s) 2 Uses for sulfisoxazole. Sulfisoxazole is used to treat or prevent infections in many different parts of the body. 3 Before using sulfisoxazole. 4 Proper use of sulfisoxazole. 5 Precautions while using sulfisoxazole. 6 Sulfisoxazole side effects. 7 Further information.

What kind of enzyme is sulfisoxazole an inhibitor of?

Can a common cold be treated with sulfisoxazole?

Your symptoms may get better before the infection is completely cleared. Sulfisoxazole will not treat a viral infection such as the common cold or flu. Do not share this medication with another person, even if they have the same symptoms you have. Antibiotic medicines can cause diarrhea, which may be a sign of a new infection.

When is the best time to take sulfisoxazole?

Sulfisoxazole works best when there is a constant amount in the blood or urine. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day.