Can I eat grapefruit with Plavix?
Clopidogrel (Plavix) normally prevents blood clots in those at high risk of having a stroke or heart attack, but grapefruit juice can make it less effective. If you are taking Plavix, you should definitely avoid grapefruit or grapefruit juice.
Can you eat grapefruit with blood thinners?
Grapefruit. Similar to leafy greens, grapefruit and grapefruit juice contain compounds that can offset the work of blood thinners. Eating grapefruit or drinking the juice can also lead to bleeding.
What can you not take with Plavix?
Nov. 17, 2009 – The FDA today warned patients not to combine Plavix with Nexium, Prilosec, and nine other drugs — including Prozac and Tagamet. The drugs may make the anti-clotting drug Plavix dangerously less effective, the FDA says. They block an enzyme in the body that turns the drug into its active form.
What heart medication can you not take with grapefruit?
Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin). Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine). Some organ-transplant rejection drugs, such as Neoral and Sandimmune capsule or oral solution (both cyclosporine).
Why is grapefruit bad with Plavix?
Cytochrome P450 (CYP) enzymes, including CYP2C19 and CYP3A4, participate in the bioactivation of clopidogrel. Grapefruit juice constituents potently inactivate intestinal CYP3A4 and have been shown to inhibit CYP2C19 as well. Therefore, the use of grapefruit juice is best avoided during clopidogrel therapy.
Can you drink coffee with Plavix?
These medications are used to slow blood clotting and include aspirin, clopidogrel (Plavix), ibuprofen (Advil, Motrin, and others), naproxen (Anaprox, Naprosyn, and others), enoxaparin (Lovenox), and more. Health experts advise caution when combining them with coffee, which can also slow blood clotting.
What foods are good to eat when you are on blood thinners?
Leafy vegetables (e.g. kale, collards, turnip greens, swiss chard, salad greens, parsley, spinach) are the highest sources of vitamin K. Other vegetables, egg yolk, soybeans, soybean and canola oils, and some nuts also provide vitamin K at lower levels.
Can I drink coffee while taking Plavix?
What pain reliever can I take with Plavix?
Usually, your doctor or pharmacist will recommend that you take acetaminophen (Tylenol) if you’re using Plavix. This is because acetaminophen is an over-the-counter (OTC) pain medication that’s least likely to cause bleeding.
Which heart medications are affected by grapefruit?
Grapefruit juice may enhance drug toxicity for antiarrhythmic agents such as amiodarone, quinidine, disopyramide, or propafenone, and for the congestive heart failure drug, carvediol. Some drugs for the treatment of peripheral or central vascular disease also have the potential to interact with grapefruit juice.
Why can’t you eat grapefruit with statins?
Grapefruit or grapefruit juice affects some statins. Do not drink grapefruit juice if you’re taking simvastatin. Grapefruit juice increases the level of simvastatin in your blood and makes side effects more likely.
Is it safe to eat grapefruit with Plavix?
However, as was stated previously, there is no known adverse reaction with Plavix and grapefruit of any kind. While you can’t take heart arrhythmia drugs such as amiodarone, and other cholesterol lowering drugs (such as Simvastatin, Lipitor and Lovastatin) with grapefruit, you can feel safe having it with Plavix.
Does grape juice interact with Plavix?
The short answer is “no.” How Does Grapefruit Juice Interact With Plavix? A 2014 study found grapefruit juice inhibits both the CYP3A4 enzyme, of which clopidogrel is a substrate, and the CYPC19 enzyme, which metabolizes the drug.
Does Plavix interact with other medications?
Plavix may interact with other blood thinners, aspirin, or nonsteroidal anti-inflammatory drugs ( NSAIDs ). Plavix may also interact with armodafinil, modafinil , fluoxetine , fluvoxamine, gemfibrozil , isoniazid , cancer medications, stomach acid reducers, antifungals, HIV medications, or seizure medications.
Can you have grapefruit juice if you take Plavix?
There are no known adverse reactions between Plavix (Clopidogrel) and eating grapefruit, or drinking grapefruit juice. Furthermore, there is no sufficient evidence that illustrates grapefruit juice, or the fruit itself would interfere with the effectiveness of Plavix.