What does Accolate do to the body?

BRAND NAME(S): Accolate. USES: Zafirlukast is used to prevent asthma symptoms and to decrease the number of asthma attacks in people 5 and older. It helps make breathing easier by reducing swelling (inflammation) in the airways.

When should you seek medical attention for side effects of Accolate?

Accolate is not a fast-acting rescue medicine for asthma attacks. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working. Take on an empty stomach, at least 1 hour before or 2 hours after a meal.

Why was zafirlukast discontinued?

Commercial reasons are cited for this decision and it is stressed that there were no safety concerns with this medicine. Zafirlukast is a leukotriene receptor antagonist and as such the closest available alternative is montelukast. Action: Clinicians should be aware of this product being discontinued.

Which is better Singulair or Accolate?

Singulair (montelukast) Although it’s less effective than inhaled steroid medications for controlling asthma, Accolate (zafirlukast) has less side effects. Makes it easier to breathe. Singulair (montelukast) has fewer side effects but doesn’t work as well as some inhaled medications for asthma and allergies.

What is the most common side effect of Accolate?

Common side effects may include: nausea, diarrhea, stomach pain; headache; or. cold symptoms such as stuffy nose, sneezing, sore throat.

How does Accolate reduce inflammation?

Accolate® (zafirlukast) is a synthetic, selective peptide leukotriene antagonist (LTRA). It is indicated to prevent asthma attacks by blocking the action of certain natural substances that cause swelling and tightening in the airways.

How long does zafirlukast stay in your system?

Zafirlukast is undetectable in urine. The mean terminal half-life ranges 8–16 hours, following linear kinetics up to doses of 80 mg.

What is the adverse effect of zileuton?

Zileuton side effects nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); skin rash, bruising, severe tingling, numbness, pain, muscle weakness; mood or behavior changes, anxiety, depression, or thoughts about suicide or hurting yourself; or.

Which are possible adverse effects of zafirlukast?

Common side effects may include:

nausea, diarrhea, stomach pain;
headache; or.
cold symptoms such as stuffy nose, sneezing, sore throat.

Is zafirlukast available in the US?

Zafirlukast (brand name Accolate) was the first cysteinyl leukotriene receptor antagonist approved in the United States. It is now approved in many other countries under other brand names.

Why is Singulair bad for you?

May cause psychiatric-type effects including agitation, aggressive behavior, anxiety, depression, abnormal dreams, and hallucinations. These have been reported in people of all ages taking Singulair. May cause dizziness or drowsiness and affect a person’s ability to drive and operate machinery.

How does Accolate affect respiratory system?

It works by blocking chemicals produced by the body called leukotrienes. Leukotrienes cause the lining of the breathing passages of the lung to swell. When used regularly, zafirlukast helps to reduce inflammation in the lining of the airways to make breathing easier.

What are the long term side effects of Accolate?

1 Abdominal or stomach pain 2 clay-colored stools 3 dark urine 4 diarrhea 5 dizziness 6 headache 7 itching 8 loss of appetite 9 nausea 10 rash

Is it safe to take Accolate during pregnancy?

Doctors or other health care professionals may prescribe it during pregnancy if it is felt that its benefits outweigh the potential unknown risks. Accolate is secreted into breast milk and should not be used by women who are breastfeeding. What are the important side effects of Accolate (zafirlukast)?

What does Accolate do to the human body?

Accolate is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen).

What to avoid if you miss a dose of Accolate?

Avoid substances that can worsen breathing problems by causing irritation or allergic reaction, such as smoke, pollen, pet dander, dust, and mold. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose.