What is the Pharmacognosy of senna?
Senna contains sennosides A and B (2.5%) based on the aglycones sennidin A and B, sennosides C and D which are glycosides of heterodianthrones of aloe-emodin and rhein are present. Others include palmidin A, rhein anthrone and aloe-emodin glycosides.
Why is senna bad for the liver?
The liver injury due to senna has been attributed to the anthraquinone derivatives present in the herbal extract, and most cases have been associated with taking excessive doses suggesting a direct hepatotoxic rather than idiosyncratic etiology.
What is biological source of senna?
The biological source of senna is dried leaflets of it. It belongs to the leguminosae plant family. It is also known as senna leaf, sennae folium, tinnevelly senna.
What is the use of Senna?
Senna is used on a short-term basis to treat constipation. It also is used to empty the bowels before surgery and certain medical procedures. Senna is in a class of medications called stimulant laxatives. It works by increasing activity of the intestines to cause a bowel movement.
What is botanical name of Senna?
Do laxatives damage your liver?
A continued increase in laxatives is typically needed to produce a bowel movement for those who abuse laxatives. Damage to internal organs can create an over-stretched or lazy colon, which can lead to colon infections, Irritable Bowel Syndrome, and liver damage .
What is the botanical source of Tinnevelly Senna?
Senna consists of the dried leaflets or fruits of Cassia senna (C. acutifolia) known in commerce as Alexandrian senna and of Cassia angustifolia commonly known as Tinnevelly senna. The senna plants are small shrubs of Leguminosae cultivated either in Somalia, the Arabian peninsula and near the Nile river.
What is the biological source of cotton?
Cotton is a soft, fluffy staple fiber that grows in a boll, or protective case, around the seeds of the cotton plants of the genus Gossypium in the mallow family Malvaceae.
How is the laxative effect of Senna exerted?
The laxative effect exerted by senna is mainly attributed to the anthraquinones which includes dianthrone glycosides, sennosides A and B, sennosides C and D. The laxative effect is exerted by acting on the lower bowel and thereby increasing the peristaltic movements of the colon by irritating the colonic mucosa.
Is it good to take Senna for constipation?
Senna is a useful laxative for either occasional use or habitual constipation. It is a popular laxative specially amongst the elderly and is devoid of the astringent after effects as observed in Rhubarb. It is reviewed to be useful during pregnancy and lactation. Senna at times may cause little abdominal discomfort like cramping.
Which is the best laxative for constipation in Nigeria?
In Nigeria, Cassia podocarpa is officially substituted. Senna is a useful laxative for either occasional use or habitual constipation. It is a popular laxative specially amongst the elderly and is devoid of the astringent after effects as observed in Rhubarb.
Are there any long term side effects of Senna?
Conclusion: There is a paucity of information in the literature regarding side effects of sennosides as a long-term therapy, and to our knowledge, this is the first review of Senna side effects in children. Senna induced dermatitis is rare, but may occur when patients need a higher dose.